Welcome to the Achaea Forums! Please be sure to read the Forum Rules
Lethargy importance without expert diagnoser?
Leth's a bit more immediately debilitating than a lot of the other affs, but any time I double up on it, I'm going to be losing affliction pressure, and the chance is usually going to be 50/50, and eventually 33/67. If I instead pick any other instill that I know they don't have, I can guarantee that I'm at least maintaining affs, and I can just avoid picking one that bloodleech hit. This gets me to cadmus faster, but I'm fully committed to pretty much ignoring hindering their offense.
How big a deal is lethargy? Especially since I ideally am trying to rush my kill in under 30s? I currently don't chance the 50/50, but if it's 33/67 I'll usually go for instilling it because of better odds, or if I'm most of the way through my instills and hence it's more likely that it was cured at some point - though by this point I can probably already cadmus, or pick a 100% aff and cadmus.