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I voted serpent just because it gives you a whole new dimension to roleplay in.
(I don't actually know if this happens.)
It's not just class that counts, house, city, order affiliations all count.
→My Mudlet Scripts
I think once you have Envenom in Subterfuge, you can secrete directly onto weapons. I don't know if you need Transcretion in Venom for that to be practical or not.I'd say play whatever you have the best character concept for. If the character doesn't click in your mind, if you can't get into their personality, it's hard to force yourself to roleplay them.